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Understand the injury simulation
Casualties: Unknown simulates limb damage and the cardiovascular system. An injury is more than a single health bar: the official description calls out wound care, infection and stabilizing blood loss.
Wound care and blood loss are connected to staying conscious during a run. Learn these systems in the tutorial before descending.
Learn dressings before an emergency
The official guidance is to bandage yourself and stabilize blood loss before losing consciousness. Use the tutorial to become familiar with crafting and dressings before starting a run.
Cave flora provides resources for patching yourself up, making the surroundings important to your survival.
Watch infection and mood too
Treating bleeding is not the only survival concern: the official description also names infected wounds as a threat.
Your mood affects survival as well. Pay attention to both physical injuries and mental state rather than treating every problem as a loss of health points.